General Pathology Catalogue

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Topography: Morphology:


General Pathology  »   INTESTINE, LARGE (XVII)  »   Dysentery (iii)


Museum No: XVII:iii:24   

Year: 1983


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Clinical data:

The patient was a 46 year old black man who presented with a history of severe diarrhoea and weakness. On examination he was severely dehydrated and shocked; he died soon after admission to hospital.


The caecum and ascending colon displayed an appearance classical of an amoebic colitis, namely the presence of numerous mucosal flask-shaped ulcers, the pathogenesis of which is ascribed to the trophozoites of Entamoeba histolytica invading the crypts and fanning out laterally over the muscularis mucosa. 


Perforation of the colon had occurred with ensuing bacterial peritonitis. Secondary involvement of the liver is frequent, as was seen in this case.

See also corresponding liver specimen  XVIII:iii:18