General Pathology Catalogue

Browse the catalogue again »

Topography: Morphology:


CASE DETAIL


General Pathology  »   INTESTINE, LARGE (XVII)  »   Dysentery (iii)

AMOEBIC COLITIS

Museum No: XVII:iii:24   

Year: 1983

 

Click thumbnails below for enlargements


Clinical data:

The patient was a 46 year old black man who presented with a history of severe diarrhoea and weakness. On examination he was severely dehydrated and shocked; he died soon after admission to hospital.

Macroscopy:

The caecum and ascending colon displayed an appearance classical of an amoebic colitis, namely the presence of numerous mucosal flask-shaped ulcers, the pathogenesis of which is ascribed to the trophozoites of Entamoeba histolytica invading the crypts and fanning out laterally over the muscularis mucosa. 

Comments:

Perforation of the colon had occurred with ensuing bacterial peritonitis. Secondary involvement of the liver is frequent, as was seen in this case.

See also corresponding liver specimen  XVIII:iii:18